| Shrek 2 | 2004 | Donkey | |||
| Haunted Mansion | 2003 | Jim Evers | |||
| Shrek 4-D | 2003 | Donkey | |||
| Daddy Day Care | 2003 | Charlie Hinton | |||
| I Spy | 2002 | Kelly Robinson | |||
| Adventures of Pluto Nash | 2002 | Pluto Nash | |||
| Showtime | 2002 | Officer Trey Sellars | |||
| Dr. Dolittle 2 | 2001 | Dr. John Dolittle | |||
| Shrek | 2001 | Donkey | |||
| Nutty Professor II: The Klumps | 2000 | Professor Sherman Klump/Buddy Love/Cletus 'Papa' Klump/Young Cletus Klump/Anna Pearl 'Mama' Jensen Klump/Ida Mae 'Granny' Jensen/Ernie Klump, Sr./Lance Perkins | |||
| "PJs, The" | 1999 | Thurgoode Orenthal Stubbs | 1999 | ||
| Saturday Night Live Christmas | 1999 | Mister Robinson | |||
| Bowfinger | 1999 | Kit Ramsey/Jiffernson 'Jiff' Ramsey | |||
| Life | 1999 | Rayford Gibson | |||
| Holy Man | 1998 | G | |||
| Doctor Dolittle | 1998 | Dr. John Dolittle | |||
| Mulan | 1998 | Mushu the Demoted One | |||
| Metro | 1997 | Scott Roper | |||
| Nutty Professor | 1996 | Professor Sherman Klump/Buddy Love/Lance Perkins/Cletus 'Papa' Klump/Anna Pearl 'Mama' Jensen Klump/Ida Mae 'Granny' Jensen/Ernie Klump, Sr. | |||
| Vampire in Brooklyn | 1995 | Maximillian/Preacher Pauly/Guido | |||
| HIStory | 1994 | Pharoah | 'Black or White' video | ||
| Beverly Hills Cop III | 1994 | Det. Axel Foley | |||
| Dangerous: The Short Films | 1993 | Pharaoh | 'Remember The Time' video | ||
| Distinguished Gentleman | 1992 | Thomas Jefferson Johnson | |||
| Boomerang | 1992 | Marcus Graham | |||
| Another 48 Hrs. | 1990 | Reggie Hammond | |||
| Harlem Nights | 1989 | Quick | |||
| What's Alan Watching? | 1989 | ||||
| Coming to America | 1988 | Prince Akeem/Clarence/Randy Watson/Saul | |||
| Beverly Hills Cop II | 1987 | Det. Axel Foley | |||
| Uptown Comedy Express | 1987 | Host | |||
| Golden Child | 1986 | Chandler Jarrell | |||
| Beverly Hills Cop | 1984 | Det. Axel Foley | |||
| Best Defense | 1984 | Lieutenant T.M. Landry | |||
| Best of the Big Laff Off | 1983 | ||||
| Trading Places | 1983 | Billy Ray Valentine | |||
| 48 Hrs. | 1982 | Reggie Hammond | |||
| "Saturday Night Live" | 1975 | Various | 1980-1984 |
Birth name: Edward Regan Murphy
Gender: Male
Spouse: Nicole Mitchell
Profession: Actor
Marital status: Married