| Ginostra | 2002 | Jessie | |||
| Jo | 2002 | Jo | |||
| Crush | 2001 | Kate | |||
| Dinner with Friends | 2001 | Karen | |||
| On the Edge | 2001 | segment Reaching Normal | |||
| Town & Country | 2001 | Eugenie Claybourne | |||
| Harrison's Flowers | 2000 | Sarah Lloyd | |||
| Reaching Normal | 1999 | Lisa | |||
| Muse | 1999 | Laura Phillips | |||
| Muppets From Space | 1999 | Shelley Snipes | |||
| Just the Ticket | 1999 | Linda Palinski | |||
| Shadrach | 1998 | Trixie Dabney | |||
| End of Violence | 1997 | Page Stockard | |||
| Michael | 1996 | Dorothy Winters | |||
| Multiplicity | 1996 | Laura Kinney | |||
| Unstrung Heroes | 1995 | Selma Lidz | |||
| 67th Annual Academy Awards | 1995 | Herself | |||
| Bad Girls | 1994 | Eileen Spenser | |||
| Four Weddings and a Funeral | 1994 | Carrie | Wedding one | ||
| Luck, Trust & Ketchup: Robert Altman In Carver Country | 1993 | Herself | |||
| Short Cuts | 1993 | Ann Finnigan | |||
| Ruby Cairo | 1993 | Bessie Faro | |||
| 65th Annual Academy Awards | 1993 | Herself | |||
| Groundhog Day | 1993 | Rita | |||
| Player | 1992 | Herself | |||
| Women & Men 2: In Love There Are No Rules | 1991 | Emily Meadows | |||
| Hudson Hawk | 1991 | Anna Baragli | |||
| Object of Beauty | 1991 | Tina | |||
| Green Card | 1990 | Bronte Mitchell Faure | |||
| Sex, Lies, and Videotape | 1989 | Ann | |||
| "Secret of the Sahara, The" | 1988 | Anthea | |||
| St. Elmo's Fire | 1985 | Dale Biberman | |||
| Greystoke: The Legend of Tarzan, Lord of the Apes | 1984 | Jane Porter |
Birth name: Rosalie Anderson MacDowell
Gender: Female
Spouse: Rhett DeCamp Hartzog
Profession: Actress/Model
Marital status: Married